ISPOR Asia Pacific 2018
Tokyo, Japan
September, 2018
GI Disorders, Multiple Diseases/No Specific Disease
Patient-Reported Outcomes & Patient Preference Studies (PRO)
Work Performance (WP), Willingness-to-Pay (WTP)
Manipis K1, Mulhern B2, Pearce A1, Haywood P1, Viney R1, Goodall S1
1University of Technology, Sydney, Sydney, Australia, 2University of Technology Sydney, Sydney, Australia
OBJECTIVES: To generate estimates of willingness-to-pay (WTP) to avoid foodborne illness (FBI), specifically two acute (gastrointestinal (GI) and flu-like illness) and four chronic (irritable bowel syndrome (IBS), Guillian-Barre syndrome, reactive arthritis, and haemolytic uraemic syndrome (HUS)) illnesses.

METHODS: A discrete choice experiment was designed. The vignettes and attributes developed were based on the literature and clinician input. Respondents were randomised to complete 20 DCE tasks for two different illnesses, with mild and severe health states, and asked to select their preferred choice set from one of two options. Attributes related to work participation, such as the ability to work and availability of sick leave were included, as were costs of treatment to alleviate symptoms, and illness duration. Choices were modelled using conditional logit regression and adjusted for condition severity.

RESULTS: A total of 1,918 respondents completed the survey. The WTP to avoid a severe illness was higher than a mild illness. The marginal WTP (MWTP) was affected by paid sick leave: for example, the MWTP to avoid mild GI increased by $139 without paid sick leave. The MWTP to avoid a mild chronic illness for one year, ranged from $344 for IBS to $901 for HUS, and when severe ranged from $964 for IBS to $1,620 for HUS. There was a substantial increase in the MWTP to avoid all the chronic conditions when the ability to work reduced and sick leave was not paid, ranging from $9,906 for severe IBS to $11,652 for severe HUS.

CONCLUSIONS: The explicit inclusion of factors that reflect productivity and compensation to workers influenced the WTP to avoid a range of FBIs for both acute and chronic conditions, and across both mild and severe conditions. The results indicate that both the severity of the FBI and consideration of the effect on productivity were important factors.